Sunday, December 29, 2013

What is chitinase?




Chitinase is widely exist in nature a kind of polysaccharide containing nitrogen biological macromolecule, the main source for crustaceans such as shrimp and crabs, insects, shell and a software of animal organs (such as squid cartilage), as well as the cell walls of fungi and so on. Its reserves in the second of natural polymer on earth, it is estimated that annual amount of synthetic biological in nature can reach 1011 tons, second only to cellulose.
Generally by refining chitin, shrimp, crab shell contains about 15% of the amino group (NH2) with 85% of the flexometallic (- COCH3). Chitin insoluble in general weak inorganic acid or organic solvent, and insoluble in lye, strong only soluble in mineral acids. Chitin has a strong hygroscopicity, moisturizing effect is also quite good, and have the function of the adsorption of heavy metal ions.
What is chitinase:  Chitinase  and chitosan, are crustaceans such as shrimp, crab, insects and other invertebrates in the shell carapace of chitin, the acetylation off (extraction) of a kind of natural polysaccharide polymer body, animal food fiber. Chitin to take off the higher the degree of acetylation, play a physiological effect is stronger, ShangHe chitin have acyl degree can reach to more than 90%. International society for medical nutrition food named a substance except sugar, protein, fat, vitamins and minerals and the five elements of the sixth largest life after life, more and more attention, therefore, it is completely different from general natural nutrition, it is chitin. Advantages: (1) the uniqueness: natural interface only positive reactive group of cellulose.

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From:Natural herbal extracts



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Friday, December 27, 2013

Information about N-(Isoxazol-5-yl)sulphanilamide



English synonyms: N - (different pbo - 5 -) aminobenzene sulfonamide; 4 - amino - N - (1, 2 - oxazole - 5 - base) benzene sulfonamide; Anhydrous disodium hydrogen phosphate; Disodium hydrogen phosphate anhydrous; Disodium phosphate
English name: N - (Isoxazol - 5 - yl) sulphanilamide
English synonyms: MONOHYDROGEN SODIUM PHOSPHATE; N - (Isoxazol - 5 - yl) sulphanilamide; SODIUM PHOSPHATE, DIBASIC; SODIUM MONOHYDROGEN PHOSPHATE; SODIUM HYDROGENHOSHATE; The SEC - SODIUM PHOSPHATE; SECONDARY SODIUM PHOSPHATE; 4 - amino - n - (1, 2 - oxazol - 5 - yl) benzenesulfonamide
CAS no. : 7758-79-4
Molecular formula: C9H9N3O3S
Molecular weight: 239.25
EINECS no. : 231-448-7
Mol files: 7758-79-4. Mol

Thursday, December 26, 2013



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From:Chemical Reagent

Information about Betamethasone Valerate




English synonyms: betamethasone valerate. Pentanoic acid betamethasone. Betamethasone valerate salt; 7 pentanoic acid betamethasone; Betamethasone valerate impurities (rapid preferential supply); 17 - valerate betamethasone
English name: Betamethasone 17 - valerate
English synonyms: VALISONE; (11 - beta, 16 - beta) - l) foxy); 17, 21 - trihydroxy - 16 - beta - methylpregna - 1, 4 - diene - 3, 20 - dione - 9 - fluoro - 11 - bet; 17 - valerate; Betamethasonevalerateester; Betnovateat; Celestoderm; Pregna - 1, 4 - diene - 3, 20 - dione, 9 - fluoro - 11, 21 - dihydroxy - 16 - methyl - 17 - ((1 - oxopenty
CAS no. : 2152-44-5
Molecular formula: C27H37FO6
Molecular weight: 476.58
EINECS no. : 218-439-3
Mol file: 2152-44-5. Mol

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From:pharmaceutical chemicals



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Thursday, December 19, 2013

Information about Betamethasone 17-Valerate



CAS no. : 2152-44-5
English synonyms: Betoid; Valison; 9 alpha Fluo; VALISONE; BEDERMIN; BETNEVAL; Beta - Val; Bextasol; Dermosol; Stanoval
Chinese name: betamethasone valerate
English synonyms: betamethasone valeric acid; 7 pentanoic acid betamethasone; Betamethasone valerate salt; Betamethasone valerate. Betamethasone 17 - pentanoic acid ester; Betamethasone valerate impurities (rapid preferential supply)
CBNumber: CB1317879
Molecular formula: C27H37FO6
Molecular weight: 476.58
MOL File: 2152-44-5. MOL
Betamethasone valerate chemical properties
Storage conditions: 2-8 ° C

Tuesday, December 17, 2013

Omeprazole sodium sterile acid suppression ability strong


Proton pump inhibitors Omeprazole sodium sterile for stomach cells, can specifically inhibit membrane composition at the top of the wall cells secretory microtubules and intracytoplasmic tubular bubble of H +, K + atpase, effectively inhibit the secretion of stomach acid. Because of H +, K + atpase is the last process of parietal cells secrete acid, so the goods acid suppression ability strong. It not only can promote gastric juice element, histamine, noncompetitive inhibition choline and food to stimulate the vagus nerve caused by gastric acid secretion, and can restrain is not affected by choline or H2 receptor blockers based gastric acid secretion, part of the H2 receptor antagonist can't suppress by two Ding Jihuan adenosine (DCAMP) stimulation caused by gastric acid secretion also have strong and long lasting effects. The goods also have inhibition to pepsin secretion, on gastric mucosal blood flow change is not obvious, also does not affect the temperature, the stomach cavity temperature, arteries and veins hemoglobin, blood pressure, oxygen partial pressure, co2 partial pressure and arterial blood pH. 
More about:Omeprazole sodium sterile manufacturer, 
From:Natural herbal extracts

Thursday, December 12, 2013



Detrusor overactivity (DO, abbreviating of the able-bodied float wall) is the a lot of accepted anatomy of UI in earlier adults. It is characterized by audacious float contractions causing an uncontrollable appetite to void. Urinary frequency, appetite bender and nocturnal bender occur. Abnormal float contractions that accompany with the appetite to abandoned can be abstinent by urodynamic studies. Treatment is float retraining,pelvic attic analysis or with drugs that arrest float contractions such as oxybutinin and tolterodine.

Studies of Ozagrel



The present abstraction was advised to appraise the furnishings of sodium ozagrel on hemostatic markers and bookish claret breeze in lacunar infarction. Ten cases of lacunar infarction in which sodium ozagrel was accustomed (administered group), 10 cases of lacunar infarction in which sodium ozagrel was not accustomed (nonadministered group), and 10 age-matched controls in which cerebrovascular diseases were absent but accident factors were agnate to those of the patients (control group) were studied. Intravenous beverage of 80 mg of sodium ozagrel was done alert a day for 2 weeks. Platelet agency 4, beta-thromboglobulin, and fibrinopeptide A were decidedly college in the administered and nonadministered groups than in the ascendancy accumulation at the time of admission. Platelet agency 4, beta-thromboglobulin, fibrinopeptide A, and thromboxane B2 were decreased decidedly by the administering of sodium ozagrel. The claret breeze in the bookish case was decidedly lower in the administered and nonadministered groups than in the ascendancy group. The claret flows about the infarcted area, in the bookish cortex, and in the bookish white amount were decidedly added by the administering of sodium ozagrel. Sodium ozagrel is advised to abatement platelet accession and access bookish claret breeze by abbreviating thromboxane A2, which has a platelet-aggregating and a vasoconstricting action. Sodium ozagrel is advised to be able in the astute appearance of lacunar infarction.

Monday, December 9, 2013

The basic information of the Enrofloxacin nicotinate




Enrofloxacin is a fluoroquinolone antibacterial awash by the Bayer Corporation beneath the barter name Baytril. Enrofloxacin is currently accustomed by the FDA for the analysis of alone pets and calm animals in the United States. In September 2005, the FDA withdrew approval of Baytril for use in baptize to amusement flocks of poultry, as this convenance was acclaimed to advance the change of fluoroquinolone-resistant strains of the bacillus Campylobacter, a animal pathogen. Fluoroquinolones such as ciprofloxacin are broadly acclimated in the analysis of animal disease.
It is a antibacterial agent. The antibacterial action of enrofloxacin is concentration-dependent, with affected bacilli corpuscle afterlife occurring aural 20–30 account of exposure. Enrofloxacin has approved a cogent post-antibiotic aftereffect for both Gram-negative and Gram-positive bacilli and is alive in both anchored and advance phases of bacterial replication.


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From:Natural herbal extracts

Thursday, December 5, 2013

Price of Propolis than gold




Propolis is an effective material for bees used to maintain the entire group health, a swarm 5 ~ 60000 year only propolis production 70-110 grams, known as the "purple gold". Propolis production period for the summer, autumn, China's rubber source roughly betulaceae, salicaceae plants, pinaceae, most of cupressaceae and cashew tree species, as well as the peach, plum, apricot, chestnut, rubber, eucalyptus and sunflower, etc. Propolis is opaque solid, the surface is smooth or rough, broken like sand granular, similar to marble appearance aspect. Golden brown, tan, and beige, sage green, dark green, a handful of deep black. Have a favorite special aromatic smell. Taste bitter, slightly spicy, stick of chewing teeth, with the hand rub knead to soften. Temperature below 15 ℃ time-varying hard, brittle, easy to crush; 36 ℃, soft, viscous and plasticity; At up to 60 ~ 70 ℃ temperature melting as viscous fluid, and isolated beeswax. Proportion vary with different plant species, generally between 1.112 ~ 1.136. Insoluble in water, slightly soluble in turpentine, partially soluble in alcohol, easily soluble in ether and chloroform. Dissolved in 95% ethanol are transparent chestnut, and particle precipitation. Pure propolis should not have other impurities.
Efficacy: it has antibacterial, beauty to raise colour, promote cells regeneration, it's doomed to propolis important position in the industry, it can not only eliminate the fungal infection, also can decompose pigment, remove wrinkles, slow aging, accelerate tissue regeneration and wound healing, the legacy of blain blain blain scar blain to imprint also have very good curative effect.
Modern research proves that the propolis contains rich and unique biological active substance, make its have antibacterial, anti-inflammatory, relieving itching, anti-oxidation, immune enhancement, blood sugar, reducing blood fat, anti-tumor and other functions, has a wide range of medical and health care function to human body, has become a national scientific research hotspot, and become the new health care products are exalted.


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From:Natural herbal extracts

Tuesday, December 3, 2013

Information about Glatiramer acetate





Chinese name: Glatiramer acetate
Chinese Synonyms: L-alanine-L-glutamic acid-L-lysine-L-tyrosine peptide polymer acetate; glatiramer acetate; Glasgow for America; glatiramer acetate 147245-92 - 9
English name: Glatiramer acetate
English Synonyms: GLATIRAMER ACETATE; l-glutamic acid polymer with l-alanine, l-lysine and l-tyrosine, acetate (salt); 511: PN: WO2010103292 PAGE: 64 claiMed sequence; L-Alanine polyMer with L-GlutaMic Acid L -Lysine L-Tyrosine Acetate; L-GlutaMic Acid peptide with L-Alanine L-Lysine L-Tyrosine Acetate Salt; L-Tyrosine polyMer with L-Alanine L-GlutaMic Acid L-Lysine Acetate; ProtiraMer; GaltiraMer acetate
CAS No.: 147245-92-9
Formula: C25H45N5O13
Molecular Weight: 623.65


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From:Natural herbal extracts

Thursday, November 21, 2013

How to define the Rnase



Ribonuclease (Ribonuclease RNase) is a kind of catalytic degradation of RNA into small fragments of nucleic acid enzymes. In all of the organisms research contains a lot of different types of ribonuclease, suggests that RNA degradation is a very original and important process. In addition to help remove the cell no longer needs to RNA, RNase also all RNA molecules involved in the mature process, which includes both carry genetic material used to guide the messenger RNA of protein synthesis, also contains the functional diversity of all kinds of non-coding RNA in the cell.

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Wednesday, November 20, 2013

What is Tegaserod/zelnorm?




Tegaserod is a 5-HT4 agonist manufactured by Novartis and sold under the names Zelnorm and Zelmac for the management of irritable bowel syndrome and constipation. Approved by the FDA in 2002, it was subsequently removed from the market in 2007 due to FDA concerns about possible adverse cardiovascular effects. Before then, it was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating, and constipation associated with irritable bowel syndrome. Its use was also approved to treat chronic idiopathic constipation.

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From:Natural herbal extracts

Sunday, November 17, 2013

Information about Toll-Like Receptor 10 Monoclonal Antibody (Clone 158C1114)



Toll-like receptor 10 is a protein that in bodies is encoded by the TLR10 gene.TLR10 has aswell been appointed as CD290 (cluster of adverse 290).
The protein encoded by this gene is a affiliate of the Toll-like receptor (TLR) ancestors which plays a axiological role in antibody acceptance and activation of congenital immunity. TLRs are awful conserved from Drosophila to bodies and allotment structural and anatomic similarities. They admit pathogen-associated atomic patterns (PAMPs) that are bidding on communicable agents, and arbitrate the assembly of cytokines all-important for the development of able immunity. The assorted TLRs display altered patterns of expression. This gene is a lot of awful bidding in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact action is not known. Multiple alternatively spliced archetype variants encoding the aforementioned protein accept been begin for this gene.


Thursday, November 7, 2013

What is Clomid (Clomiphene)?




Clomid (Clomiphene) capsule is hormone drug resistance. This product to stimulate ovulation is not yet fully understood. Because of this product is weak for estrogen excited and strong antagonism dual function, stimulate ovulation may be in the hypothalamus, the first advantage of antagonism, through a competitive occupy the hypothalamus estrogen receptor, interfered with endogenous estrogen negative feedback, prompt production luteal hormone and follicle-stimulating hormone secretion to increase, then stimulate follicle growth and mature follicle, estrogen to release a quantity to increase, by the positive feedback gonadotropin release of peak before ovulation, ovulation.

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From:Natural herbal extracts

Tuesday, November 5, 2013

What is Methandrostenolone?





Methandrostenolone (trade names Averbol, Dianabol, Danabol), aswell accepted as metandienone (INN) or methandienone, is an orally-effective anabolic steroid originally developed in Germany and appear in the US in the aboriginal 1960s by Ciba Specialty Chemicals.
Methandrostenolone is a controlled actuality in the United States and Western Europe and charcoal accepted a part of bodybuilders. An injectable anatomy is awash online from United States based companies. Methandrostenolone is readily accessible after a decree in countries such as Mexico (under the barter name Reforvit-b), and is aswell getting bogus in Asia and abounding East European countries.


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From:Natural herbal extracts

What is 2-(chloromethyl)-4-methylquinazoline?


CAS:109113-72-6

Molecular formula:C10H9ClN2

Molecular weight:192.64486

Density:

1.251 g/cm3

Melting Point:61 - 63 °C

Boiling Point:240.039 °C at 760 mmHg

Flash Point:122.14 °C

Application:intermediates of Linagliptin

Product description:2-(chloromethyl)-4-methylquinazoline is a pale yellow to yellow powder, it is used as the pharmaceutical intermediates.

Sunday, November 3, 2013

A brief introduction of Platinum wire




A silver-white brownish adored aspect occurring worldwide, usually adulterated with added metals such as iridium, osmium, or nickel. It is adaptable and malleable, does not burn in air, and is acclimated as a agitator and in electrical components, jewelry, dentistry, and electroplating. It is awful aggressive to bane and electrochemical attack. Diminutive amount 78; diminutive weight 195.09; melting point 1,772°C; baking point 3,827°C; specific force 21.45 g / cm^3.
Standard abstention is 99.95%. Also accessible as 99.99% pure, 99.999% pure, and adulterated with Iridium or Gold. Platinum is accessible in wire, sheet, rod, tube, casting pieces, crumb and shapes. Many items are in banal or accept abbreviate artifact times. Surepure can draw Platinum wire to beneath 0.001 inch bore and cycle area to beneath 0.001 inch thick. Surepure has sputtering targets of assorted sizes.



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From:Chemical Reagent

Friday, November 1, 2013

The basic information of the 7-Epiclindamycin hydrochloride



CAS NO. 55-17431-9
Molecular formula: C18H34Cl2N2O5S
Molecular weight: 461.444 g/mol
Moore files: 17431-55-9. - mole
Boiling point: 628.1 ° C to 760 MMHG
Flash: 333.6 ° C
The evaporation enthalpy: 106.52 the focal per mole
The steam pressure: 2.07 e 18 ° C 25 mmHg


Wednesday, October 30, 2013

What is 3,5-Dichloro-4-pyridinone?

CAS:17228-70-5
Molecular formula:C5H3Cl2NO
Molecular weight:163.99
Appearance:White or yellowish crystalline powder
 Use:The intermediate of Cefazedone, cefazolin
Product description:3,5-Dichloro-4-pyridinone is a white or yellowish crystalline powder, and used as the intermediate of Cefazedone.

What is Camellia sinensis?



Camellia sinensis is the breed of bulb whose leaves and blade buds are acclimated to aftermath the accepted cooler tea. It is of the brand Camellia (Chinese: 茶花; pinyin: Cháhuā, literally: "tea flower"), a brand of beginning plants in the ancestors Theaceae. White tea, chicken tea, blooming tea, oolong, pu-erh tea and atramentous tea are all harvested from this species, but are candy abnormally to attain altered levels of oxidation. Kukicha (twig tea) is aswell harvested from Camellia sinensis, but uses twigs and stems rather than leaves. Common names cover tea plant, tea shrub, and tea timberline (not to be abashed with Melaleuca alternifolia, the antecedent of tea timberline oil).
There are two above varieties acclimated for tea, Chinese tea, Camellia sinensis var. sinensis, and Assam tea, Camellia sinensis var. assamica.



Friday, October 25, 2013

What is Rapamycin?




Rapamycin (RAPA) is a new type of large ring lactone class immunosuppressants. Rapamycin factor receptor blocking signal transduction through different cells, block the T cell and other cell from G1 phase to S phase process, thereby immunosuppressive effect into full play. From the point of clinical application, rapamycin has good anti-rejection effect, and with cyclosporine A (CsA) and FK506 immune inhibitors have good synergy, is A kind of good curative effect, low toxicity, no new immunosuppressant nephrotoxicity. In March 2010, the United States, according to a study at the university of Texas rapamycin can be used in the treatment of alzheimer's disease, the drug composition are also present in the Easter island secretion of the bacteria in the soil.

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From:Lactic acid bacteria

Wednesday, October 23, 2013

What is Tacrolimus?




Tacrolimus and FK506, from Streptomyces (Streptomyces tsukubaensis) isolated from the fermentation product, its chemical structure is 23 yuan ring lactone class antibiotic. As a powerful new immunosuppressants, mainly by inhibiting the release of interleukin - 2-2 (L), fully inhibit the role of T cells, a ring of spore (CsA) 100 times stronger. In recent years, as a line of the liver and kidney transplantation medicine, in 14 countries such as Japan, the United States. Clinical trials showed that the heart, lung, intestine, bone marrow transplant in the application has a good curative effect. And FK506 in the treatment of atopic dermatitis (AD), systemic lupus erythematosus (SLE) and autoimmune autoimmune diseases such as eye disease also play an active role.
Indications: liver, heart, kidney and bone marrow transplant patients with immunosuppressive drugs of choice, after transplantation rejection of traditional immunosuppression solution resistance, also can choose the drug. Adverse reactions are similar to those of cyclosporine.


Monday, October 21, 2013

What is Cefodizime?


Cefodizime is a third bearing cephalosporin with a ample spectrum of antibacterial activity. Administered intravenously or intramuscularly, cefodizime 1 to 4g circadian for an boilerplate of 7 to 10 canicule produced analytic cure in 80 to 100% of patients (adults, aged or children) with high or lower respiratory amplitude infections or urinary amplitude infections, and in allusive trials cefodizime was as able as added third bearing cephalosporins. A individual dosage of cefodizime 1 or 2g is aswell advantageous in alleviative lower urinary amplitude infections, decidedly apprehensible infections, with a amount of analytic success of 72 to 88%. Urogenital gonorrhoea, whether acquired by β-lactamase bearing or non-β-lactamase bearing Neisseria gonorrhoeae, is actual finer advised by individual dosage analysis with intramuscular cefodizime 0.25 to 1g (virtually 100% cured). Basic abstracts from a baby amount of patients announce that cefodizime may aswell be advantageous in the analysis of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or analysis of surgical infections.
The analytic adeptness of cefodizime in allegory with added third bearing cephalosporins is above to that predicted from in vitro results. This above action of cefodizime may be accompanying to the almost continued abolishment half-life of the biologic or its adeptness to adapt some functions of the allowed arrangement — a potentially important award apprehension added investigation.
Cefodizime is able-bodied acceptable and has a tolerability contour agnate to added associates of its chic with systemic adverse contest getting primarily gastrointestinal or dermatological.
Thus, bound allusive studies announce cefodizime has the abeyant to become a advantageous another to accepted antimicrobial analysis for the analysis of a array of infections. Cefodizime may be added acceptable to administrate than some added agents of its chic as it may be accustomed already or alert daily. While there are no trials comparing cefodizime to added third bearing cephalosporins in immunosuppressed populations, basic advice indicates cefodizime may be advantageous in this group.
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Friday, October 18, 2013

Iloperidone metabolite P95 of basic information



English name: Iloperidone Carboxylic Acid
English synonyms: Iloperidone Carboxylic Acid; 4 - [3 - (4 - (6 - Fluoro - 1, 2 - benzisoxazol - 3 - yl) - 1 - piperidinyl] propoxy] - 3 - Methoxybenzoic Acid; P 95-12113; Iloperidone metabolite P95
CAS no. : 475110-48-6
Molecular formula: C23H25FN2O5


Tuesday, October 15, 2013

Some indications Ubenimex





Indications: Ubenimex can enhance immune function, used for cancer chemotherapy, radiotherapy adjuvant treatment of senile immune defects. Can be combined with chemotherapy, radiotherapy and combined application of leukemia, multiple myeloma, myelodysplastic syndrome, and hematopoietic stem cell transplantation, and other solid tumors.
Toxicology: Ubenimex from Streptomyces (Streptomyces ofivorecticuli) separating the resulting culture medium containing compounds competitively inhibit aminopeptidase B (aminopeptidase N/CD13) and leucine peptidase (Leucineamino-Peptidase). Enhance T cell function, the NK cell killing vitality, and to lead to increased synthesis of colony-stimulating factor to stimulate the regeneration of bone marrow cells and differentiation. This product can interfere with the metabolism of tumor cells, inhibition of tumor cell proliferation, apoptosis and activation of human immune function, stimulating cytokine production and secretion of anti-tumor effect of promoting cell generation and proliferation.


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From:Lactic acid bacteria

Friday, October 11, 2013

Teriparatide Acetate role and side effects






Teriparatide Acetate for patients suffering from severe osteoporosis , the drug is also being evaluated for the treatment of osteogenesis imperfecta aspects of efficacy in clinical trials.
There should not be elevated to patients at risk of suffering from osteosarcoma open with Teriparatide Acetate. Such patients include those suffering from Paget's bone disease (Paget's Disease of bone, osteitis deformans ) in patients with unexplained elevated serum alkaline phosphatase in patients in patients not yet closed epiphyseal plate , or related to bone radioactive treatment of patients.
Side effect
The most common side effects are nausea, leg cramps and dizziness . The main risk for Teriparatide Acetate is to increase the risk of suffering from osteosarcoma , at least in rats, the results of experimental studies to see is this . After the listing of the drugs , there have been very little about the risk of bone tumors and reported cases of osteosarcoma .
Mechanism
Teriparatide Acetate part of the human parathyroid hormone , the amino acid sequences 1-34 , complete human parathyroid hormone containing 84 amino acids . Endogenous parathyroid hormone in bone and kidney the primary regulator of calcium and phosphorus metabolism . PTH to increase the calcium concentration in serum , accompanied by an increase in calcium concentration , bone absorption of calcium is also part of the increase . Thus, the long-term elevated PTH , will consume bone saved. However , exposure to intermittent PTH activates osteoblasts, osteoclasts more so . Thus, once daily injections of teriparatide has a secondary net effect of new bone formation leading to bone density increased inorganic matter .
Teriparatide Acetate is the first one , but also to the current position of the only one FDA-approved treatment for osteoporosis, a drug to stimulate new bone formation .



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From:Natural food additive

Wednesday, October 9, 2013

Ni-Mo hydrodesulfurization agent -related information




Ni-Mo hydrodesulfurization agent is activated to acclimatized gas, abounding petroleum gas,refinery gas.Strong acerbic sites on the credible of mesoporous MCM-41 were generated by ion-exchanging siliceous MCM-41 with attenuated HNO3 band-aid (0.5 M). The XRF affirmation indicates that a lot of of the sodium cations absolute in MCM-41 can be removed by the proton exchange, and dealuminization was empiric during the proton exchange. The acidity of the mesoporous abstracts was characterized by bureau of NH3-TPD and the Hammett indicators. It is arise that new able acerbic sites (-5.6 > H0 > -8.2) were generated afterwards the ancient 2 h of ion bargain and that the after ion exchanges had little aftereffect on the absinthian properties. XRD patterns of the mesoporous abstracts advertise that the analysis of siliceous MCM-41 was bigger by HNO3 ion exchange. If Ni-Mo hydrodesulfurization abettor sulfides were authentic on the able solid acerbic (H+-MCM-41), top accomplishment in the hydrodesulfurization (HDS) of dibenzothiophene (DBT) was observed. However, the HDS action was decreased while the selectivity of biphenyl (BP) was increased, if H+-Si-MCM-41 was ion exchanged with Na2CO3 aqueous solution. TPR profiles of the authentic Ni-Mo oxides accede that the absinthian accomplishments of the supports abundantly admission the hydrogenation activities of the bimetallic oxides. The top accomplishment of H+-MCM-41-supported Ni-Mo catalysts may be attributed to the added hydrogenation activity.
The role of nickel in the action of bottomless Ni-Mo hydrodesulfurization abettor hydrodesulfurization catalysts
A alternation of bottomless nickel-molybdenum sulfide catalysts accoutrement the ambit 0–100 atom% nickel has been able by connected coprecipitation. Highly broadcast Ni3S2 is appropriate to play a role in hydrogen activation, appointment protons and electrons to the MoS2, and this may anatomy the o rigin of the accessory mechanism. The acceptable roles of the apostle are summarized.


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From:Catalyst chemistry

Tuesday, October 8, 2013

Etridiazole basic information





CAS No.: 2593-15-9
English name: ETRIDIAZOLE
English Synonyms: ETMT; KOLAN; Dwell; Koban; TRUBAN; Banrot; Etcmtb; MF-344; om2424; ETHAZOL
Chinese name: dimethylphenyl acrylate
Chinese Synonyms: Soil benomyl; chlorazol spirit; pause between interest; chlorazol Spirit / soil benomyl; dimethylphenyl acrylate; 5 - ethoxy-3 - trichloromethyl-1 ,2,4 - thiadiazole
CBNumber: CB0145031
Formula: C5H5Cl3N2OS
Molecular Weight: 247.53
MOL File: 2593-15-9.mol
Dimethylphenyl acrylate Chemical Properties
Flash Point: 154.5 ° C
Storage conditions: 0-6 ° C
Safety Information
Hazard Codes: T, N
Risk Codes: 21/22-23-40-50/53-20/21/22
Safety Instructions: 36/37-38-45-60-61
RIDADR: UN2810 6.1/PG 2
RTECS Number: XI3875000
Health Hazard: Burning produces toxic chlorine, sulfur oxide and nitrogen oxide gases
Storage features: Treasury ventilated low-temperature drying; separate storage and food ingredients
Extinguishing Media: Dry chemical, foam, sand


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From:Herbal extract

Thursday, August 29, 2013

Sulfaclozine Sodium Uses




Purpose:
(1) poultry, poultry coccidiosis Sulfachloropyrazine role characteristics and similar Sulfaquinoxalinum, and possessed a stronger antibacterial effect, and even treat fowl cholera and fowl typhoid, so the most suitable for treatment with the outbreak of coccidiosis .
Application Sulfachloropyrazine not affect the host immunity against coccidiosis.
(2) Other This product is also quite effective coccidiosis free, can be used per 1000kg feed, add 600g Sulfachloropyridazine adjacent triazine sodium, and even fed 5 to 10 days.
On lamb coccidiosis, each lkg body weight, can be 3% solution 1.2mL orally, once every 3 to 5 days.

Note:
(1) This product is far more toxic Sulfaquinoxalinum low, but the long-term application still appears sulfa drug poisoning symptoms, so chickens can only be recommended concentrations, once every three days, to a maximum of 5 days.
(2) In view of the majority of our farms, the application of sulfa drugs (such as SQ, SM2, etc.) has been for decades, coccidia sulfonamide resistance may have even cross-resistance, so that in case of poor efficacy phenomenon, should be replaced drugs.
(3) more than 16 weeks of laying hens and chickens disabled.
(4) the withdrawal period, turkeys 4 days broiler one day.


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From:Natural herbal extracts

Tuesday, August 27, 2013

L-Cystine introduction of related purposes



L-cystine is a nutritional supplement. For milk breast milk. Is a non-essential amino acids. Constitute the skin and hair is essential substances, can promote surgery and trauma treatment. Stimulate hematopoietic function, and promote leukocyte formation. Promote oxidation of body cells and restore function, but also can be used for cosmetic additives can promote wound healing, prevention and treatment of eczema and other allergic skin effect.
Purpose:
1 for biochemical research. Preparation of biological medium. For biochemistry and nutrition research, medicine can promote oxidation of body cells and restore function, increased white blood cells and prevent pathogen growth and so on. Mainly used for a variety of alopecia. Also used for dysentery, typhoid, influenza and other acute infectious diseases, asthma, neuralgia, eczema and various diseases such as poisoning, and to maintain the role of protein conformation. Also used as a food flavoring agent.
(2) biochemical reagents for biological media preparation. Amino acid infusion and also an important component of the composite amino acid preparations
3 for nutritional supplements, is conducive to animal development, weight gain, and liver and kidney function, improve the quality of fur.
4 can be used for cosmetic additives, can promote wound healing and prevent skin allergies and eczema and so on.




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From:Natural herbal extracts

Sunday, August 25, 2013

Arimadex (Anastrozole) pharmacy medical knowledge

Arimadex (Anastrozole) tablets tradename Rui Ting, Arimidex, is a potent non-steroidal aromatase inhibitors. May reduce plasma levels of estrogen, resulting in inhibition of mammary tumor growth. Clinic for postmenopausal women with advanced breast cancer.
Product Use:
Use one: potent and selective aromatase inhibitors triazole, can inhibit the cytochrome P-450 enzyme aromatase depend thereby blocking the biosynthesis of estrogen, and estrogen to stimulate the growth of breast cancer cells the main factor.
Uses two: the treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy in women after menopause advanced breast cancer.
Pharmaceutical medical knowledge:
Indications: For anastrozole after tamoxifen and other anti-estrogen therapy still can not control in postmenopausal women with advanced breast cancer. On estrogen receptor-negative patients, if their right tamoxifen showed positive clinical response, consider using anastrozole.
ACTION: Anastrozole is a potent and selective non-steroidal aromatase inhibitors. Inhibit postmenopausal patients with adrenal androstenedione generated into estrone, which significantly reduced plasma levels of estrogen, resulting in inhibition of mammary tumor growth. In addition, anastrozole right adrenal corticosteroids or aldosterone generate no significant effect.
Pharmacokinetics: oral anastrozole absorbed quickly in the body about 40% of anastrozole and plasma protein binding, the majority metabolized into inactive products were excluded from the urine, about 10 per cent of the prototype anastrozole excluded from the urine . According to reports, healthy male volunteers after oral administration of 1mg, time to peak plasma concentration was 1.22 ± 0.46 hours, peak plasma concentration was 9.99 ± 3.24ng/ml, elimination half-life of 35.96 ± 14.17 hours.
Dosage: Tablets: orally once a day, every one (1 mg), with mild to moderate hepatic function or mild renal impairment in patients with generally Needless to adjust the dose.

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Thursday, August 22, 2013

Tranexamic Acid pharmacological effects





Tranexamic Acid Chemical name: aminomethylcyclohexane acid, trans-4 - (aminomethyl) - cyclohexane carboxylic acid. Mainly used for acute or chronic, localized or systemic fibrinolysis hyperthyroidism caused by a variety of bleeding. Disseminated intravascular coagulation due to high secondary fibrinolysis, in the absence of heparin, before, careful.

Pharmacological effects:
Fibrinolytic phenomenon and the body under physiological or pathological state fibrinolytic, increased vascular permeability, etc., but also with fibrinolysis induced reaction of the organism, such as a variety of bleeding symptoms and the incidence of allergy associated with the development and healing. This product can inhibit plasmin role, and show bleeding, anti-allergic, anti-inflammatory effect.
1 antifibrinolytic action of enzymes
Tranexamic acid to plasmin and plasminogen with fibrin on the part of the lysine affinity binding site (LBS) is strongly adsorbed, inhibition of plasmin, plasminogen and fibrin binding and thus strongly inhibit fibrin by plasmin induced decomposition; addition, serum macroglobulin and other anti-plasminogen in the presence of tranexamic acid antifibrinolytic effect is more obvious
Pharmacokinetic properties: bioavailability of 34%, half-life of 3.1h


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From:Natural herbal extracts

Tuesday, August 20, 2013

BM-MSCs separation method




BM-MSCs are bone marrow stem cells, bone marrow hematopoietic stem cells (HSC) is not only mechanical support role, but also secrete a variety of growth factors (such as IL-6, IL-11, LIF, M-CSF and SCF, etc.) to support hematopoiesis.
MSC currently used methods include separation of whole bone marrow and density gradient centrifugation method that is based on whole bone marrow stem cells in low serum medium planted with adherent edge features, the medium was changed regularly adherent cells are not removed, so as to achieve purification and expansion MSC additional purposes. Density gradient centrifugation of the cells in the bone marrow that are based on the proportion of different components, mononuclear cells adherent culture. Essentially no much difference between the two. With in-depth understanding of MSC surface antigen, and anyone using immunological methods such as flow cytometry, immunofluorescence beads, etc. be isolated and purified. But after flow sorting or magnetic bead cell appeared after some problems such as slow growth, coupled with the high cost and technical difficulty, to some extent limited the widespread application of these methods.


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From:Natural herbal extracts

Tuesday, August 13, 2013

Amiodarone Hydrochloride traits and uses




Appearance: white to light yellow crystalline powder, almost odorless, tasteless, melting point 153 ~ 158 ℃. Soluble in chloroform, soluble in ethanol, slightly soluble in acetone, insoluble in water.
Action and Uses: Amiodarone Hydrochloride for the anti-angina drugs can selectively dilating coronary blood flow, while reducing myocardial oxygen consumption, heart rate, atrioventricular conduction velocity decreased with β-blockers similar effect. For supraventricular and ventricular tachycardia, paroxysmal atrial fibrillation and flutter, WPW syndrome, but also for chronic paroxysmal tachycardia, coronary insufficiency and angina pectoris.



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From:Natural herbal extracts

Monday, August 12, 2013

Ertapenem Sodium for injection some indications



Indications: Ertapenem Sodium for the treatment of adults by the following bacteria caused by susceptible strains of the following moderate to severe infections. (See DOSAGE AND ADMINISTRATION) · secondary abdominal infections: Escherichia coli, Clostridium, slow Eubacterium, Peptostreptococcus, Bacteroides fragilis, Bacteroides Gibbs, B. ovatus, Bacteroides thetaiotaomicron or simplex caused by Bacteroides. · Complicated skin and appendages infections: Staphylococcus aureus (methicillin-susceptible strains only refers to), Streptococcus pyogenes, Escherichia coli, or those caused by Peptostreptococcus. • Community-acquired pneumonia: Streptococcus pneumoniae (penicillin-susceptible strains only refer to, including the merger of bacteremia cases), Haemophilus influenzae (refers only to the β-lactamase-negative strains), or Moraxella catarrhalis bacteria cause persons. · Complicated urinary tract infections, including pyelonephritis: the Escherichia coli or Klebsiella pneumoniae caused by. · Acute pelvic infections, including postpartum endometritis, abortion infection after infection and obstetrics: the Streptococcus agalactiae, Escherichia coli, Bacteroides fragilis, puzzled sugar Porphyromonas bacteria Peptostreptococcus or double Lupuleiwo caused by Escherichia. · Bacteremia.
For the separation and identification of pathogens and determine its susceptibility to ertapenem should be properly taken for bacteriological examination of specimens. In obtaining the results of these checks before you can start using this for empirical treatment; Once inspection results, respond antibiotic regimen adjusted accordingly. In order to reduce the formation of bacterial resistance and to ensure the product's efficacy and other antibacterial drugs, this product can only be used for the treatment or prevention of an identified or highly suspected infections caused by sensitive bacteria. When obtaining bacterial culture and drug susceptibility testing results, should be selected and adjusted accordingly antibiotic treatment. In the absence of the test results before, according to the local epidemiology and susceptibility bacterial characteristics, select the empiric treatment.



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From:Natural herbal extracts

Tuesday, August 6, 2013

Fucus vesiculosus can be used for weight loss




Fucus vesiculosus is a brownish-green atramentous algae that is added frequently accepted as float blow or kelp. It is built-in to the western shores of the Mediterranean Sea and to the North Atlantic coasts. Although it has abounding uses, alignment from ammunition to aliment for cattle, it is aswell a accepted homeopathic remedy. It may be acclimated to anticipate goiter or thyroid disease, to advance weight loss, to amusement rheumatism, and as an antiviral treatment.
This abyssal bulb is both adjustable and strong. Although brownish-green if alive, fucus vesiculosus turns atramentous if it dries out. It has a able odor and an abhorrent taste. This alga contains polysaccharides, polyphenols, and minerals, accurately iodine. The polysaccharides about plan to activate the allowed system, while the iodine works to activate the thyroid.
Many humans affirmation that fucus vesiculosus promotes weight accident through the use of a application or capsules fabricated from the alga. It is believed that back the alga is top in iodine, iodine levels in the physique will access by arresting the capsules or cutting the patch. The physique uses iodine to accomplish the thyroid hormone, which manages the body’s metabolism. Consequently, users achievement there will be an access in the assembly of the thyroid hormone by cutting the application and aswell an access in the body’s metabolism. By accretion the body’s metabolism, a being may be able to lose weight after appliance and dieting.


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From:Natural herbal extracts

Monday, August 5, 2013

REPERTAXIN L-LYSINE SALT basic information



CAS Number: 446024-42-6
English name: REPERTAXIN L-LYSINE SALT
English Synonyms: R-(-) -2 - (4-Isobutylphenyl) propionyl MethansulphonaMide L-lysine salt
CBNumber: CB1504464
MF: C20H35N3O5S1
Molecular Weight: 429.57
MOL File: Mol file
REPERTAXIN L-LYSINE SALT Chemical Properties
Storage conditions: 2-8 ° C
Solubility: H2O: 52 mg / mL
form: lyophilized powder
Safety Information
WGK Germany: 3



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Thursday, August 1, 2013

1,3-Benzodioxole-5-ethanamine basic information



CAS: 74341-77-8
English name: 1,3-Benzodioxole-5-ethanamine, alpha-methyl-N-propyl-, hydrochloride
English Synonyms: (±)-N-Propyl-3 ,4-methylenedioxyamphetamine hydrochloride; 1,3-Benzodioxole-5-ethanamine, alpha-methyl-N-propyl-, hydrochloride
CBNumber: CB91238137
MOL File: 74341-77-8.mol
Synonyms: Einecs 245-825-9; RARECHEM AN KA 0317; 7-METHOXY-1 ,3-BENZODIOXO-5-ETHANAMINE; 7-methoxybenzo-1 ,3-dioxole-5-ethylamine; 7-METHOXY-1, 3 - BENZODIOXOLE-5-ETHANAMINE
Molecular formula: C10H13NO3
Molecular weight: 195.22
Product description: This product is light yellow crystal powder and its melting point is 195-198 centidegree. It is mainly used to compound Cefprozil, Cefixime and so on.


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From:Natural herbal extracts

Tuesday, July 30, 2013

Acyclovir impurity some utility





Acyclovir impurity is a synthetic purine nucleoside analogs. Caused by herpes simplex virus is mainly used for a variety of infections that can be used in primary or recurrent skin, mucous membranes, genital herpes infection and immunodeficiency HSV infection occurred. For the treatment of HSV encephalitis drug of choice to reduce morbidity and mortality are better than vidarabine. Can be used for herpes zoster, EB virus, and immune deficiency complicated by infections such as chickenpox. Local only for skin, Acyclovir impurity skin absorb less.

Indications:
1 herpes simplex virus infection: oral genital herpes infection for primary and recurrent cases; cases of recurrent oral on the materials used for prophylaxis. Injection for the immunocompromised. Onset and recurrent mucocutaneous infections and prevention of recurrent cases; also used for the treatment of herpes simplex encephalitis.
2 herpes zoster: oral for normal immune function with herpes and immunocompromised mild cases of treatment. Injections for severe immunocompromised patients with herpes treatment.
3 immunocompromised chickenpox treatment.
4 topically to herpes simplex virus-induced early genital herpes infection and immunodeficiency self-limiting mucocutaneous herpes simplex initial treatment and recurrence.
5 with its sodium treatment of acute retinal necrosis. Nucleotide antiviral drugs for the treatment of:
① herpes simplex keratitis;
② herpes simplex;
③ with herpes;
④ with its sodium salt treatment of acute retinal necrosis. Mainly for the herpes simplex virus and zoster virus causes superficial, deep keratitis.


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From:Poly peptides

Sunday, July 28, 2013

Lysipressin Acetate some of the information


Chinese name: Lysipressin Acetate
Chinese Synonyms: Acetic acid Lai vasopressin; lysine vasopressin (LYSPRESSIN); Lypressin; Lai vasopressin; CYS-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2 (DISULFIDE BRIDGE: CYS1-CYS6); acetic acid lysine vasopressin 50-57-7; acetic acid lysine vasopressin LYSIPRESSINACETATE
English name: Lypressin
English Synonyms: (8-lysine) vasopressin; 8-l-lysine-vasopressi; 8-l-lysinevasopressin; diapid; l-lysinevasopressin; lysinepitressin; postacton; syntopressin
CAS Number: 50-57-7
Formula: C46H65N13O12S2
MW: 1056.22
EINECS Number: 200-050-5
Mol File: 50-57-7.mol
Lysipressin Acetate are mammals such as pigs, etc. One of the posterior pituitary hormone secretion, which consists of hypothalamic nucleus of the hypothalamus produces and then by axonal transport to the posterior pituitary, and then secreted by the posterior lobe. Containing a nine amino acid residues of the active peptides, because of which the two cysteines linked by a disulfide as a cystine (Cys-Cys), also known as timing octapeptide. In addition from the posterior pituitary extract, but also to synthetic, it has anti-diuretic and blood pressure rise, therefore called antidiuretic hormone (antidiuretic hormone) or vasopressin (vasopressin)



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From:Poly peptides

Friday, July 26, 2013

What is Aviptadil Acetate?



Cas No. 40077-57-4
Name :Aviptadil Acetate
Sequence : His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Molecular Formula : C147H238N44O42S
Molecular Weight : 3325.87
Purity (HPLC) :98.0%
Appearance : White powder
Single Impurity(HPLC) : 1.0%
Amino Acid Composition : 10% of theoretical
Peptide Content(N%): 80%(by %N)
Water Content(Karl Fischer) : 6.0%
Acetate Content(HPIC): 15.0%
Mass Balance 95.0~105.0%



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From: Poly peptides

Thursday, July 25, 2013

Protirelin Acetate Product Overview


Name: Protirelin Acetate
ProtirelinAcetate active substances: This product is to stimulate the pituitary secretion of thyroid-stimulating hormone (TSH) and prolactin (PRL) CAS NO :24305-27-9 sequence: Pyr-His-Pro-NH2 Molecular formula: C16H22N6O4 MW: 362.39
1 The diagnosis of Graves' disease.
2 the differential diagnosis of thyroid dysfunction lesion (primary or secondary pituitary insufficiency).
3. Determine the hypothalamus - pituitary - thyroid axis function tests pituitary reserve function. Product parameters:
1.Purity (HPLC)
≥ 99%. And ≥ 99.5% 2.Appearance
White powder3.Single Impurity (HPLC)
1.0% max4.Amino Acid Composition
± 10% of theoretical5.Peptide Content (N%)
≥ 80.0% 6.Water Content (Karl Fischer)
≤ 5.0% 7.Acetate Content (HPIC)
≤ 10.0% 8.MS (ESI)
Consistent9.Mass Balance



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Wednesday, July 24, 2013

Alarelin Acetate inspection methods



Characters: Alarelin Acetate is a white or almost white powder; odorless, hygroscopic This product is dissolved in methanol, slightly soluble in 1% acetic acid solution dissolved specific rotation of this product, accurately weighed, add 1% acetic acid solution, dissolved and diluted quantitatively per 1ml solution containing 5mg, determined by law (Appendix Ⅵ E), by water, no matter acetate calculated specific rotation of -46 ° to -56 °. Absorption coefficient of this product, accurately weighed, dissolved in water and diluted quantitatively containing 0.1mg per 1ml of the solution, according to the UV - visible spectrophotometry (Appendix Ⅳ A), the absorbance was measured at a wavelength of 279nm by water, No acetic acid was calculated, the absorption coefficient (E 1% / 1cm) of 52-57.
Clarity and color of solution of this product 20mg, 2ml dissolved in water, the solution should be clear and colorless; such as color, with yellow on the 2nd standard colorimetric solution (Appendix Ⅸ A), not deeper. Take some acetic acid, accurately weighed, add diluent [Mobile phase A-mobile phase B (95:5)] dissolved and diluted 1ml each containing about 10mg solution as the test solution; Another ice acetic acid amount, accurately weighed, add Diluent 1ml each containing about 0.60mg solution as the reference solution. High performance liquid chromatography Governance (Appendix Ⅴ D) determination, with octadecylsilane bonded silica as a filler, phosphoric acid (phosphate take 0.7ml, add water 1000ml, with sodium hydroxide to adjust pH to 3.0) as mobile phase A, methanol as mobile phase B, gradient elution, detection wavelength was 210nm. Number of theoretical plates calculated peak acetate, not less than 2000. Gradient elution procedure is as follows: Time (min) Mobile phase A (%) mobile phase B (%) 0 95 5 5 50 50 20 50 50 25 95 5 precise amount of the reference solution and the test solution 20μl, were injected liquid chromatograph, record the chromatograms, the external standard method with peak area calculation. Acetic acid containing not more than 7.5%. Amino acid ratio of this product, plus 6mol / L hydrochloric acid solution at 110 ℃ after 24 hours hydrolysis with a suitable amino acid analysis ceremony measured by HPLC, the test with each amino acid alanine molar ratio should meet the following requirements : 0.7 to 1.0 of serine, glutamic acid is 0.9 to 1.1, proline 0.8 to 1.0, 0.9 to 1.1 leucine, tyrosine 0.9 to 1.1, 0.9 to 1.1 histidine, arginine 0.9 to 1.1. For substances of this product, add water containing 0.5mg per 1ml of solution as the test solution; precise amount of 1ml, 100ml flask, diluted with water to the mark, shake, as the control solution. According to the determination under chromatographic conditions, take control solution 20μl into the liquid chromatograph, adjust the sensitivity, the principal component chromatographic peak height of about 50 per cent of full scale; precise amount of the reference solution and the test solution 20μl , were injected into the liquid chromatograph, record the chromatograms to the main component peak retention time of 2 times, the test solution chromatogram, except the solvent peak, a single impurity peak area no larger than the control solution peak area of ​​2 times. The impurity peak area and peak area shall not be greater than the control solution 5 times (the main component of any less than the control solution peak area 0.05 times the peak to be negligible). Water to remove the goods, according to the determination (Appendix Ⅷ M first method A). Water containing not more than 7.0%.



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Sunday, July 21, 2013

The Lysipressin Acetate Products


Name: Lysipressin Acetate
English Name: Vasopressin ,8-L-lysine-
Cas Number: 50-57-7
Alias: 9 - Lai vasopressin LVP; acetate Lai vasopressin; Lai vasopressin
Formula: C46H65N13O12S2
MW: 1056.22
EINECS: 200-050-5
Chemical properties:
Lysipressin Acetate traits:
This product is a synthetic vasopressin Lai colorless and transparent solution pH3.7 ~ 4.3, containing sodium acetate buffer, antibacterial agent triclosan methyl tert-butyl alcohol and sodium chloride. Vasopressin has a natural variety of biological activity per unit depends vasopressin antidiuretic effect equivalent to the human "fine vasopressin" half of its vasoconstrictor properties only in the application of high doses only apparent. Duration of action than diabetes insipidus stop short, only about 4 hours.
Lysipressin Acetate use: suitable for medium and mild pituitary diabetes insipidus.
Description:
1.Lysipressin Acetate overview:
The goods are mammals such as pigs, etc. One of the posterior pituitary hormone secretion, which consists of hypothalamic nucleus of the hypothalamus produces and then by axonal transport to the posterior pituitary, and then secreted by the posterior lobe. Containing a nine amino acid residues of the active peptides, because of which the two cysteines linked by a disulfide as a cystine (Cys-Cys), also known as timing octapeptide. In addition from the posterior pituitary extract, but also to synthetic, it has anti-diuretic and blood pressure rise, therefore called antidiuretic hormone (antidiuretic hormone) or vasopressin (vasopressin).
2 physiological functions:
Mainly to promote renal tubular reabsorption of water; also causes including coronary artery, pulmonary artery, including systemic small artery contraction, blood pressure. Elevated blood pressure and heart activity in view of the adverse, it is mainly used in clinical deficiency caused by the anti-diuretic hormone treatment of diabetes insipidus, but renal polyuria invalid.
3 lysine vasopressin (50-57-7) Usage and dosage:
Can be administered subcutaneously, intramuscularly; also be made of the pituitary nasal spray powder and other products. Each time the nasal spray one or two, three to five times a day. Stimulation of the nasal mucosa than diabetes insipidus stop powder for the light.
4 adverse reactions and precautions:
 Because no heterosexual protein, so allergic reactions than animal extracted vasopressin small. Common ulcerative epistaxis. Coronary artery aneurysms and epilepsy hanged.
5 Formulation:
5mL / bottle (each containing 50 mL vasopressin units).



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Wednesday, July 17, 2013

About the Eptifibatide Acetate



Brief Description
Eptifibatide(Integrilin)AcetateMolecular Formula: C35H49N11O9S2
Molecular Weight: 831.96Sequence: (Mpr-Harg-Gly-Asp-Trp-Pro-Cys)-NH2SPECIFICATIONS:1 .Appearance:Whitepowder
2.SpecificOpticalRotation(c=1,HAc,ByAnhydrous,AceticAcid-free) :-78~-88°
Product Attributes
Related attributes of Eptifibatide Acetate:
Place of Origin:Sichuan China (Mainland)Purity:more than 98%
Detailed Description
Detailed addition to Eptifibatide Acetate:
Eptifibatide(Integrilin) Acetate
Molecular Formula: C35H49N11O9S2
Molecular Weight: 831.96
Sequence: (Mpr-Harg-Gly-Asp-Trp-Pro-Cys)-NH2
SPECIFICATIONS:
1 .Appearance :White crumb
2 .Specific Optical Rotation(c=1,HAc,By Anhydrous, Acetic Acid-free) :-78~-88°
3 .Water Content(Karl Fischer) :≤8.0%
4 .Acetate Content(by HPLC) :≤15.0%
5 .Amino Acid Composition :±10% of abstract
6 .Purity(by HPLC) :≥98.0%
7 .Single Impurity(by HPLC) :≤1.0%
8 .Peptide Content(by %N) :≥80%
9 .Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
10.Bacterial Endotoxins :≤5EU/mg
Packing:plastic canteen (dedicated for peptide packing) or bottle vial, abundance according to customer's detail requirement.
Storage:a cool(2~8 amount C) & dry abode adequate from light, accumulate amalgamation abutting if not in use.



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