The protein encoded by this gene is a affiliate of the Toll-like receptor (TLR) ancestors which plays a axiological role in antibody acceptance and activation of congenital immunity. TLRs are awful conserved from Drosophila to bodies and allotment structural and anatomic similarities. They admit pathogen-associated atomic patterns (PAMPs) that are bidding on communicable agents, and arbitrate the assembly of cytokines all-important for the development of able immunity. The assorted TLRs display altered patterns of expression. This gene is a lot of awful bidding in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact action is not known. Multiple alternatively spliced archetype variants encoding the aforementioned protein accept been begin for this gene.
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