Wednesday, May 20, 2015

Introduction of Hypericin


Hypericin is a naphtodianthrone, a red-coloured anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.
The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that hyperforin is responsible for the MAOI effect.
CAS:     548-04-9
Molecular Formula:C30H16O8
Formula Weight:504.44
from:Acridine Raw Material

Monday, May 18, 2015

what is the Cholesterol?



Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals.It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol is an important component for the manufacture of bile acids, steroid hormones, and fat-soluble vitamins including Vitamin A, Vitamin D, Vitamin E, and Vitamin K. Cholesterol is the principal sterol synthesized by animals, but small quantities are synthesized in other eukaryotes, such as plants and fungi. It is almost completely absent among prokaryotes, which include bacteria. Although cholesterol is an important and necessary molecule for animals, a high level of serum cholesterol is an indicator for diseases such as heart disease.
CAS:57-88-5
Molecular Formula:C27H46O
Formula Weight:     386.65
from:Acridine Raw Material

Wednesday, May 13, 2015

what is the uses of Ethylenediaminetetraacetic acid?


Ethylenediaminetetraacetic acid, widely abbreviated as EDTA (for other names, see Table) is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve scale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA.
Lead poisoning and heavy metal toxicity
Chelation therapy using EDTA is the medically accepted treatment for lead poisoning. Injected intravenously and once in the bloodstream, EDTA traps lead and other metals, forming a compound that the body can get rid of in the urine. The process generally takes 1 - 3 hours. Other heavy metal poisonings treated with chelation include mercury, arsenic, aluminum, chromium, cobalt, manganese, nickel, selenium, zinc, tin, and thallium. Chelating agents other than EDTA are also used to clear several of these substances from the bloodstream.
Heavy metal toxicity in humans has been associated with many health conditions, including heart disease, attention deficit/hyperactivity disorder (ADHD), Alzheimer's disease, immune system disorders, gastrointestinal disorders (including irritable bowel syndrome, or IBS), and autism.
Digoxin toxicity
EDTA has also been used to treat digoxin toxicity, although most doctors prefer to use other methods. In this case, EDTA helps remove excess levels of digoxin, a medication that is used to treat abnormal rhythms of the heart.
from:Acridine Raw Material

Monday, May 11, 2015

what is the Quinine sulfate dihydrate?



Name:Quinine sulfate dihydrate CAS:6119-70-6 Molecular Formula:C40H48N4O4·H2SO4·2H2O Formula Weight:782.96 Description: Melting point:233-235 ºC Chemical property:white crystalline powder Product Categories:Antiparasitic / Antiprotozoal / AnthelminthicVoltage-gated Ion Channels;Monovalent Ion Channels; Potassium Channel Modulators;Antiparasitic / Antiprotozoal / AnthelminthicBiochemicals and Reagents from:Acridine Raw Material

Monday, April 27, 2015

Overview of Polydatin


Polydatin is the glycoside of Resveratrol (sc-200808) originally isolated from the Chinese herb Polygonum cuspidatum. The compound has been shown to inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. Myocardial cell, white blood cell, vascular smooth muscle cell, and endothelial cell studies report that Polydatin can inhibit ICAM-1 expression, elevate Ca2+, weaken white blood cell-endothelial cell adhesion, and activate KATP channels.
CAS:27208-80-6
Molecular Formula:C20H22O8
Formula Weight:390.38
Appearance: white powder
Specification: 98%(By HPLC)  
Melting Point : 130-140
Solubility: soluble in methanol
Storage:Preserve in tight, light-resistant containers,protected from moisture, and store at controlled room temperature.
from:Acridine Raw Material

Thursday, April 23, 2015

what is the Copper telluride?


Copper telluride is a gold and silver products in the production process, copper, tellurium and other elements.
Copper telluride is a black crystal powder at room temperature is relatively stable in the air. telluride of copper is not only important inorganic materials, but also
Tellurium and copper resources are stored in the excellent form. In H2SO4 solution, replacement of Te with Cu copper telluride, generated so many metal tellurium
Ion separation and enrichment are very high. Cu replacement Te, Te can be + 4 + 6, price or prices, can generate Cu2 Te, that is, not
By the valence of tellurium. in the oxidant in the presence of copper telluride with acid or alkali chemical reaction, which is the separation and recovery of Cu and
Te basis. In short, tellurium and copper compounds at higher temperatures with each other in the recovery of tellurium from the solution is very unique.
from:Rare Metals

Monday, April 20, 2015

what is the role of Eugenol ?


The Eugenol is an organic compound with the formula C10H12O2. The IUPAC name of this chemical is 2-methoxy-4-prop-2-enylphenol. With the CAS registry number 97-53-0, it is also named as phenol, 2-methoxy-4-(2-propen-1-yl)-. The product's categories are Antioxidant; Biochemistry. Besides, it is a clear colorless pale yellow or amber-colored liquid, which should be stored in a dark and cool place.It will be darkens and thickens on exposure to air. Also darkens with age. Eugenol may decompose on exposure to light. Insoluble in water.It reacts with strong alkalis. Eugenol is incompatible with strong oxidizers. This includes ferric chloride and potassium permanganate.
The Eugenol is used in perfumeries, flavorings, essential oils and in medicine as a local antiseptic and anesthetic. It is also a key ingredient in Indonesian kretek (clove) cigarettes. It was used in the production of isoeugenol for the manufacture of vanillin, though most vanillin is now produced from phenol or from lignin. Eugenol is attractive to males of various species of orchid bees, so it is commonly used as bait to attract and collect these bees for study. Eugenol derivatives or methoxyphenol are used in formulating insect attractants and UV absorbers, biocides, analgesics, and antiseptics. They are also used in manufacturing stabilizers and antioxidants for plastics and rubbers.
When you are using Eugenol, please be cautious about it as the following:
It is harmful if swallowed and may cause sensitisation by inhalation and skin contact. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, Eugenol is irritating to eyes, respiratory system and skin and limited evidence of a carcinogenic effect. When you are using it, wear suitable protective clothing, do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) and avoid contact with skin and eyes.
from:Natural standard substance