Hypericin is a naphtodianthrone, a red-coloured anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.
The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that hyperforin is responsible for the MAOI effect.
CAS: 548-04-9
Molecular Formula:C30H16O8
Formula Weight:504.44
from:Acridine Raw Material
No comments:
Post a Comment