Where to find Polymyxin B Sulphate?

Polymyxin B Sulphate is antibiotic derived from a strain of Bacillus polymyxa. Polymyxin B Sulphate is a sulfate salt of the least toxic member of the polymixin group. Polymyxin B (Sulphate) is bacteriocidal for many gram negative bacteria. Polymyxin B (Sulphate) is a cationic, basic peptide contains fatty acid D-6-methyloctan-1-oic acid and amino acids L-threonine and L-diaminobutyric acid. Polymyxin B Sulphate is used in the treatment of various systemic, urinary tract, otic, ophthalmic and cutaneous infections due to susceptible gram -ve bacteria. Polymyxin B (Sulphate) is administered orally, parentrally and topically, but nowadays, rarely used parentrally due to its potential for causing nephrotoxicity and/or neurotoxicity. Polymyxin B (Sulphate) is more commonly administered as either a topical or otic agent in combination with neomycin or bacitracin. Polymyxin B (Sulphate) is also available in ophthalmic solutions in combination with either trimethoprim B or in combination with bacitracin and neomycin. Polymyxin B is also used in combination with neomycin as a urinary tract irrigant. Polymyxin B was originally approved by the FDA in 1951.
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