Rapamycin (RAPA) is a new type of large ring lactone class immunosuppressants. Rapamycin factor receptor blocking signal transduction through different cells, block the T cell and other cell from G1 phase to S phase process, thereby immunosuppressive effect into full play. From the point of clinical application, rapamycin has good anti-rejection effect, and with cyclosporine A (CsA) and FK506 immune inhibitors have good synergy, is A kind of good curative effect, low toxicity, no new immunosuppressant nephrotoxicity. In March 2010, the United States, according to a study at the university of Texas rapamycin can be used in the treatment of alzheimer's disease, the drug composition are also present in the Easter island secretion of the bacteria in the soil.
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From:Lactic acid bacteria
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