Thursday, August 22, 2013
Tranexamic Acid pharmacological effects
Tranexamic Acid Chemical name: aminomethylcyclohexane acid, trans-4 - (aminomethyl) - cyclohexane carboxylic acid. Mainly used for acute or chronic, localized or systemic fibrinolysis hyperthyroidism caused by a variety of bleeding. Disseminated intravascular coagulation due to high secondary fibrinolysis, in the absence of heparin, before, careful.
Pharmacological effects:
Fibrinolytic phenomenon and the body under physiological or pathological state fibrinolytic, increased vascular permeability, etc., but also with fibrinolysis induced reaction of the organism, such as a variety of bleeding symptoms and the incidence of allergy associated with the development and healing. This product can inhibit plasmin role, and show bleeding, anti-allergic, anti-inflammatory effect.
1 antifibrinolytic action of enzymes
Tranexamic acid to plasmin and plasminogen with fibrin on the part of the lysine affinity binding site (LBS) is strongly adsorbed, inhibition of plasmin, plasminogen and fibrin binding and thus strongly inhibit fibrin by plasmin induced decomposition; addition, serum macroglobulin and other anti-plasminogen in the presence of tranexamic acid antifibrinolytic effect is more obvious
Pharmacokinetic properties: bioavailability of 34%, half-life of 3.1h
More about:Tranexamic Acid manufacturer
From:Natural herbal extracts
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