Lentinula is a small genus of wood-inhabiting agarics. The neotropical species Lentinula boryana (= L. cubensis) is the type species. However, the best known species is L. edodes, the shiitake. The genus was erected by Franklin Sumner Earle in 1909.
Lentinan, a polysaccharide isolated from shiitake, is thought to be causative for numerous of the mushroom's beneficial effects. But a clinical trial failed to show any benefit of an oral shiitake extract in the treatment of prostate cancer.
An injectable class of lentinan is exploited because genus Cancer discussion inwards about commonwealths, but it has not been evaluated in large cogitations. Fashionable vitro analyzes carried with lentinan have indicated its anticancer effectuates fashionable colon malignant neoplastic disease cells, these consequences may result from its ability to suppress cytochrome P450 1A enzymes that are known to metabolize pro-carcinogens to active forms. Initially during trials, it is always necessary to tract the temperature in various parts of the autoclave as well as in the pocketed substratum along intromission of a thermocouple inside the substrate. After the substrate reach 121°C , it is needed to conserve at 121°a hundred because half-hour.
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