Flucytosine is a broad-spectrum antifungal agents about acclimated in aggregate assay (often with amphotericin B) for the assay of fungal infections such as cryptococcal meningitis.
Flucytosine should not be acclimated as a alone abettor in aggressive fungal infections acquired by almost anemic antifungal action and the accelerated development of resistance, but in aggregate with amphotericin B and / or azole antifungals such as fluconazole or itraconazole.
The affair about the toxicity (suppression of cartilage marrow, alarmist dysfunction) and the development of the bane absolute the use of attrition flucytosine, abnormally as monotherapy. It can aswell be acclimated for the assay of chromomycosis (chromoblastomycosis) if astute strains could could cause infection.
more about: 5-Flucytosine
from: Pharmaceutical Ingredients
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