Thursday, December 12, 2013

Studies of Ozagrel



The present abstraction was advised to appraise the furnishings of sodium ozagrel on hemostatic markers and bookish claret breeze in lacunar infarction. Ten cases of lacunar infarction in which sodium ozagrel was accustomed (administered group), 10 cases of lacunar infarction in which sodium ozagrel was not accustomed (nonadministered group), and 10 age-matched controls in which cerebrovascular diseases were absent but accident factors were agnate to those of the patients (control group) were studied. Intravenous beverage of 80 mg of sodium ozagrel was done alert a day for 2 weeks. Platelet agency 4, beta-thromboglobulin, and fibrinopeptide A were decidedly college in the administered and nonadministered groups than in the ascendancy accumulation at the time of admission. Platelet agency 4, beta-thromboglobulin, fibrinopeptide A, and thromboxane B2 were decreased decidedly by the administering of sodium ozagrel. The claret breeze in the bookish case was decidedly lower in the administered and nonadministered groups than in the ascendancy group. The claret flows about the infarcted area, in the bookish cortex, and in the bookish white amount were decidedly added by the administering of sodium ozagrel. Sodium ozagrel is advised to abatement platelet accession and access bookish claret breeze by abbreviating thromboxane A2, which has a platelet-aggregating and a vasoconstricting action. Sodium ozagrel is advised to be able in the astute appearance of lacunar infarction.

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